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منابع مشابه
Targeted drug delivery to treat pain and cerebral hypoxia.
Limited drug penetration is an obstacle that is often encountered in treatment of central nervous system (CNS) diseases including pain and cerebral hypoxia. Over the past several years, biochemical characteristics of the brain (i.e., tight junction protein complexes at brain barrier sites, expression of influx and efflux transporters) have been shown to be directly involved in determining CNS p...
متن کاملLiver Targeted Drug Delivery System
Targeted drug delivery or site-specific drug delivery system has the potential to increase local drug concentrations and thereby increase the effectiveness of the medicines with fewer side effects. Liver diseases especially liver cancer is one of the most prevalent cancers, with a high mortality. Due to high toxicity and poor specificity of the chemotherapeutic agents the present method of trea...
متن کاملTargeted Drug Delivery Systems for Lung Cancer
In the present scenario, lung cancer is one of the most prevalent and malignant cancer especially among the smoking group of people. The targeted delivery of chemotherapeutic agents to the lungs represents a novel therapeutic approach in lung cancer. Lung is an ideal route for administration of anticancer drug as it provides larger alveolar surface area, low thickness of epithelial barrier & ex...
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ژورنال
عنوان ژورنال: Drug Design, Development and Therapy
سال: 2019
ISSN: 1177-8881
DOI: 10.2147/dddt.s216660